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Closalic Ointment 30gm
Generic Name Clobetasol Propionate 0.05% + Salicylic Acid 3%
Company Name: Ziska Pharmaceuticals Ltd.
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✅ Description:
Indications of Closalic 30 Ointment
The use of this ointment is recommended for the treatment of hyperkeratotic and dry corticosteroid-responsive dermatoses, including psoriasis, chronic atopic dermatitis, neurodermatitis (lichens Simplex, Chronicus), lichen planus, eczema (including nummular eczema, hand eczema, and eczematous dermatitis), seborrheic condition.
Pharmacology of Closalic 30 Ointment
high potency corticosteroid. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing the release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.
Dosage & Administration of Closalic 30 Ointment
For external use only.
Interaction of Closalic 30 Ointment
There has been no report of interaction with Clobetasol Propionate ointment and cream. There are no known interactions of Salicylic Acid when used as indicated.
Contraindications
ClobetasolPropionatev is contraindicated in patients with hypersensitivity to Clobetasol Propionate.
Side Effects of Closalic 30 Ointment
As with other topical corticosteroids, prolonged use of large amounts of Clobetasol Propionate or treatment of extensive areas can result in sufficient systemic absorption to produce the features of hypercortisolism.
Pregnancy & Lactation
Topical administration of corticosteroids to pregnant animals can cause abnormalities in fetal development. The relevance of this finding to human beings has not been established. The safe use of Clobetasol Propionate during lactation has not been established.
Precautions & Warnings
Not for prolonged use in high concentrations and on large areas of the body.
Storage Conditions
Keep in a dry place away from light and heat.
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